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Product Name    |    Neotame

Appearance    |    White powder

Grade    |    Food grade

Formula    |    C20H30N2O5

Type    |    Powder

CAS No    |    165450-17-9

HS Code    |    2924299090

Shelf life    |    Two years

Packing    |    25kg/drum, 16tons/20’FCL


What is Neotame?
Neotame has been developed as a sweetener with a high degree of sweetness and is obtained by N-alkylating aspartame, an existing sweetener. It is 7,000 to 13,000 times and about 30 to 60 times sweeter than sugar and aspartame respectively.
Compared with other sweeteners, neotame is rarely detected in food, indicating that it is not widely used in the food industry. The reasons may be as follows:
1. Neotame is a new product that has been used in my country since 2003. Compared with other traditional sweeteners, it takes a certain amount of time to be promoted and accepted;
2. Neotame is a patent of the American Nut Company. The monopoly production before the end of 2013 resulted in a high price of neotame, and the cost-effectiveness advantage was not obvious. After the expiration of the U.S. patent, many manufacturers have not yet had time to adjust the formula;
3. Neotame has the characteristic of delayed sweetness, but it can be improved by compounding with other sweeteners;
4. Its sweetness is too high, and the limit allowed in food is low. It is inconvenient to weigh a small amount when used alone, and it is difficult for small and medium-sized enterprises to control the dosage.

NAME: Neotame
CAS NO.: 165450-17-9
EINECS NO.: 253-404-6
HS CODE: 2924299090
SPECIFICATION; Items Specifications
Appearances White crystalline powder
Assay ( on dry basis)% 97.0-102.0
PH Value 5-7
Loss on dying % ≤0.2
Melting range 81℃-85℃
Lead ≤2ppm
Residue on ignition % ≤0.1
As, mg/kg ≤0.3
Total aerobic bacteria cfu/g ≤250
Water content % ≤5.0
Coliform ≤10mpn/g
PACKAGING: 25kg/bag or carton
QUANTITY/CONTAINER: 15MT/20'FCL without pallets
HANDLING&STORAGE: Kept in dry, cool and shaded place, avoid moisture
Neotame has been developed as a sweetener with a high degree of
sweetness and is obtained by N-alkylating aspartame, an existing
sweetener. It is 7,000 to 13,000 times and about 30 to 60 times sweeter
than sugar and aspartame respectively. Neotame is said to have
superior stability to existing sweeteners and not torelease
phenylalanine under normal storage conditions.

Applications of Neotame Sweetener:
①Application in various beverages
a. Carbonated drinks
Neotame can last for 16 weeks in cola-type carbonated drinks, which is consistent with the shelf life of low-energy carbonated drinks on the market. It can also be used in lemonade, root juice and other drinks.
b. Non-carbonated drinks
Neotame can be used in hot-filled lemon tea, solid powder drinks, yogurt and other foods, and its properties are very stable and of good quality in these foods.

②Application in dairy products
Neotame can be used in dairy products, ice cream and other frozen desserts. When used in such products, after the shelf life of such products has expired, studies have found that only 2% of neotame is lost, which is acceptable for the product. It has no impact on sex, while other sweeteners rarely reach this level. Neotame is especially suitable for the production of yogurt.

③Application in baked goods
Unlike aspartame, neotame can remain stable under transient high temperature conditions, so it can be used in various baked goods such as cookies, cakes, and chocolate cakes. For example, in cake production, after baking at a high temperature of 450°C, 85% of neotame is still present; and when stored at 25°C and a relative humidity of 60% for 5 days, only 4% of neotame is lost. In fact, even if A 20% loss will not have an impact on the product.

④Application in chewing gum
Since the energy value of neotame is almost 0 and it does not cause dental caries, it is suitable for the production of sugar-free chewing gum. It is not only suitable for diabetics, but also has no harmful effect on teeth. The stability of neotame in chewing gum can be improved by microencapsulation, and the two-layer coating of modified starch and hydroxypropyl methylcellulose can prevent it from degrading during 52 weeks of storage.

⑤Application in table sweeteners
Because neotame has no hygroscopicity and low energy, it is very suitable as a table sweetener. Studies have shown that neotame can be stored for at least 156 weeks when used as a table sweetener.

⑥Application in ice cream
Ice cream made with neotame has good dissolution characteristics and structure, and its sweetness is pure and has no aftertaste.

Neotame Side Effects:
Recently, a research report titled "The artificial sweetener neotame negatively regulates the intestinal epithelium directly through T1R3-signaling and indirectly through pathogenic changes to model gut bacteria" was published in the international magazine Frontiers in Nutrition, from Jahangal University and others Scientists from the agency revealed for the first time that neotame not only directly damages the intestinal epithelial barrier, but may also induce lesions in the originally healthy intestinal flora, triggering a series of chain reactions and shaking the foundation of human health.
In the article, researchers pointed out that neotame can cause friendly bacteria in the intestines to transform into potential health threats, increase biofilm formation, and enhance the ability of pathogens to adhere to and invade cells. Worryingly, neotame is commonly found in beverages, foods and chewing gum. In in vitro studies, researchers identified a series of pathogenic responses in Escherichia coli and Enterococcus faecalis after exposure to neotame, including biofilm formation, adhesion of pathogenic bacteria to cells, and invasiveness. Enhancement etc.
Some of the latest artificial sweeteners are 1,000 times sweeter than sugar. Their ultra-high sweetness means that even trace additions may have a profound impact on the intestinal microecology and trigger metabolic disorders and inflammatory diseases. Professor Chichger said that people are now increasingly aware of the impact of sweeteners such as saccharin, sucralose and aspartame on human health. Previous research results have shown that they may cause some damage to the intestinal wall, and It will damage the "good bacteria" formed in the intestinal tract of the body.
Researchers say this can lead to a range of potential health problems, including diarrhea, enteritis, and even infections such as sepsis if the bacteria enter the bloodstream.

Neotame vs Aspartame:
Unlike aspartame, neotame can be used with certain reducing sugars, such as glucose, fructose, lactose, etc.; it can also be used with aldehyde-based flavoring substances, such as vanilla, cinnamon, lemon, etc. It is used in candies, cereals, jelly and other products. Research shows that neotame has good properties when used in these foods.

Where to Buy Neotame in Bulk?
Neotame is a commonly used food additive and ingredient popular in many countries. As a professional Neotame supplier and manufacturer, Hangzhou Focus Corporation has nearly 10 years of experience in supplying and exporting Neotame  from China. You can safely choose to buy Neotame  from Hangzhou Focus Corporation. If you have any questions or concerns, please feel free to contact us and we will get back to you within 1 business day.

  1. If you have needs please contact us

Established in 2011, with 2 self-owned factories in 2015, Hangzhou Focus Corporation specializes in manufacture and trade of various kinds of food additives, including Neotame.We offer wholesale prices for bulk purchases, even for small quantities, and offer a free sample to potential customers.

  1. If you have needs please contact us


Q: Are you trading company or manufacturer ?

A: We are manufacturer.

Q: How long is your delivery time?

A: Generally it is 5-10 days if the goods are in stock. or it is 15-20 days if the goods are not in stock, it is according to quantity.

Q: Do you provide samples ? is it free or extra ?

A: Yes. We are pleased to provide the free sample while the freight cost may need you to undertake.but we will refund this freight cost when you place an order.

Q: What is your terms of payment ?

A: The payment method is flexible, we support various payment methods: TT/LC/CAD, all are acceptable, usually we use 30% TT IN ADVANCE,70% ONCE CARGOS READY.

If you have another question, pls feel free to contact us.

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